NCT02693106

Evaluation of the Ketogenic Potential of Different Diet Supplements

Stimulating the Ketogenesis by Using Nutritional Supplements

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 13 (actual)
• Sponsor: Université de Sherbrooke · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Evaluate the capacity of different dietary supplements to increase ketone production in healthy adults.

Detailed description

The aim of this study is to evaluate the capacity of different dietary supplements to increase ketone production in healthy adults. Each supplement (leucine, butyrate, octanoate, carnitine or butter fraction rich in MCT) is evaluated for a period of 4-hour during which multiple blood samples are taken in order to measure ketone production.

Conditions

• Healthy Adults

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Control	Visit corresponding to a standardize breakfast taken alone (control visit) followed by a period of 4-hour with multiple blood sampling.
DIETARY_SUPPLEMENT	Leucine	Visit corresponding to a standardize breakfast with 5 g of leucine followed by a period of 4-hour with multiple blood sampling.
DIETARY_SUPPLEMENT	Butyrate -	Visit corresponding to a standardize breakfast with 3.6 g of butyrate followed by a period of 4-hour with multiple blood sampling.
DIETARY_SUPPLEMENT	Butyrate +	Visit corresponding to a standardize breakfast with 7.2 g of butyrate followed by a period of 4-hour with multiple blood sampling.
DIETARY_SUPPLEMENT	Octanoate -	Visit corresponding to a standardize breakfast with 5 g of octanoate followed by a period of 4-hour with multiple blood sampling.
DIETARY_SUPPLEMENT	Octanoate +	Visit corresponding to a standardize breakfast with 10 g of octanoate followed by a period of 4-hour with multiple blood sampling.
DIETARY_SUPPLEMENT	Carnitine	Visit corresponding to a standardize breakfast with 1.95 g of carnitine followed by a period of 4-hour with multiple blood sampling.
DIETARY_SUPPLEMENT	Butter fraction	Visit corresponding to a standardize breakfast with 65 g of butter fraction followed by a period of 4-hour with multiple blood sampling.

Timeline

• Start date: 2013-07-01
• Primary completion: 2015-06-01
• Completion: 2015-06-01
• First posted: 2016-02-26
• Last updated: 2020-03-25
• Results posted: 2020-03-25

Locations

1 site across 1 country: Canada