NCT02692235

Carnitine Supplementation and Skeletal Muscle Function

Carnitine Supplementation and Skeletal Muscle Function in Aging

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 28 (actual)
• Sponsor: Gdansk University of Physical Education and Sport · Academic / Other
• Sex: All
• Age: 65 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Research project objectives The primary aim of the current research project is to use carnitine supplementation as the anti-inflammatory intervention for exploring the relationship between inflammation and associated with aging reduction of skeletal muscle mass. Hypothesis The carnitine supplementation modulates the blood cytokines concentration. Anti-inflammatory intervention delay the reduction of skeletal muscle mass associated with aging

Detailed description

Volunteers over 65 years old (n=40) are supplemented either with carnitine or placebo for 24 weeks. Before the start, in the mid-point, and after finishing the supplementation the following primary outputs variables are performed: body composition analysis (InBody720), maximal isokinetic knee extensor peak torque (Biodex System 4 Pro), blood cytokines and carnitine concentration, blood lipid profile.

Conditions

• Sarcopenia

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	carnitine	1500 mg/d l-carnitine-l-tartrate
DIETARY_SUPPLEMENT	placebo	isonitrogenous

Timeline

• Start date: 2016-02-01
• Primary completion: 2017-03-01
• Completion: 2017-07-01
• First posted: 2016-02-26
• Last updated: 2019-05-23
• Results posted: 2019-05-09

Locations

1 site across 1 country: Poland