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UnknownNCT02692118

Inflammatory Mediators in Early Sepsis

Inflammatory Mediators in Sepsis as Indicator for Infection vs Inflammation

Status
Unknown
Phase
Study type
Observational
Enrollment
60 (estimated)
Sponsor
University Hospital Tuebingen · Academic / Other
Sex
All
Age
18 Years – 85 Years
Healthy volunteers
Not accepted

Summary

Sepsis is still a challenge for clinicians since the detailed pathomechanism are still unknown and until now early markers for sepsis are not defined yet. Immunological pathways and new mediators defined in animal models are not yet investigated in patients with sepsis. Therefore the investigators will measure new mediators in patients with septic shock.

Detailed description

Semaphorins 1 to 7 will be determined in Blood of patients with early septic shock. Concentration will be compared with blood concentration of postoperative patients suffering systemic inflammatory response syndrome (SIRS).

Conditions

Timeline

Start date
2016-12-01
Primary completion
2022-06-01
Completion
2022-09-01
First posted
2016-02-25
Last updated
2021-06-07

Locations

1 site across 1 country: Germany

Source: ClinicalTrials.gov record NCT02692118. Inclusion in this directory is not an endorsement.