NCT02691897

Melatonin's Effects on Treatment Of Diabetes Mellitus

The Effects of Melatonin on Serum Glucose Levels of Patients With Type 2 Diabetes Mellitus

• Status: Unknown
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Shiraz University of Medical Sciences · Academic / Other
• Sex: All
• Age: 20 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to assess the efficacy and safety of melatonin in control of blood sugar in patients with type 2 diabetes mellitus (DM).

Detailed description

Diabetes mellitus (DM) is a major public health problem with increasing worldwide incidence. The main causes for increase in incidence of DM are inactivity, obesity and changes of dietary habits. Investigators think that the changes in the awake-sleep cycle may also contribute to higher incidence of DM in recent years. Melatonin is an important component of the circadian system. Numerous experimental studies have demonstrated that melatonin has many beneficial actions.Melatonin is a potent antioxidant, reduces inflammatory process, lowers blood pressure, improve lipid profiles. Collectively, these data suggest that melatonin may be useful in control of blood sugar in patients with DM. The aim of this study is to assess the efficacy of melatonin in control of blood sugar in patients with type 2 DM.

Conditions

• Diabetes Mellitus

Interventions

Type	Name	Description
DRUG	Melatonin	Melatonin 3mg once daily at bedtime
DRUG	Placebo	Placebo 1 tablet once daily at bedtime

Timeline

• Start date: 2019-07-01
• Primary completion: 2020-05-01
• Completion: 2020-07-01
• First posted: 2016-02-25
• Last updated: 2019-04-08

Locations

1 site across 1 country: Iran