Trials / Completed
CompletedNCT02688751
Contrast Enhanced Ultrasound, Endoleak Detection Following EVAR v1.3
Contrast Enhanced Ultrasound Endoleak Detection Compared To Time-Resolved Computer Tomography Angiography in High Risk Endovascular Aneurysm Repair (EVAR) Surveillance Patients.
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 30 (actual)
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust · Other Government
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
A single site cross-sectional comparison of paired diagnostic imaging modalities. This study will show the sensitivity and specificity of CEUS in detecting the various types of endoleaks, in comparison to tCTA, following EVAR. It will collect data to allow comparison of diagnostic accuracy across modalities including CDU, CEUS and tCTA. It will collect time taken to perform the various types of scan, to allow healthcare costs to be calculated for each imaging modality.
Detailed description
This study will show the sensitivity and specificity of CEUS in detecting the various types of endoleaks, in comparison to tCTA, following EVAR. It will collect data to allow comparison of diagnostic accuracy across modalities including CDU, CEUS and tCTA. It will collect time taken to perform the various types of scan, to allow healthcare costs to be calculated for each imaging modality. Collected data will be analysed regarding two novel hypothesised methods of using CEUS information: The first is recording temporal delay between contrast in graft and contrast in endoleak to define endoleak type. Potentially this could be used as a faster method of defining endoleak type in a surveillance programme. The second is to identify/refute correlation between CEUS contrast to appear in endoleak vs tCTA contrast to appear in endoleak. If an association can be established, CEUS timings could potentially then be used to time 'standard' CTA phases to improve CTAs diagnostic accuracy.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| RADIATION | time-resolved CT Angiography | A multi-phase contrast CT |
| PROCEDURE | Contrast Enhanced Ultrasound | A ultrasound scan with micro bubble contrast injection |
Timeline
- Start date
- 2016-01-20
- Primary completion
- 2018-03-20
- Completion
- 2018-03-20
- First posted
- 2016-02-23
- Last updated
- 2022-06-09
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT02688751. Inclusion in this directory is not an endorsement.