Trials / Completed
CompletedNCT02688582
Target-controlled Infusion Model for Cefepime
A Study to Evaluate the Predictive Performance of a Target-controlled Infusion Model for the Administration of Cefepime to Intensive Care Patients
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 21 (actual)
- Sponsor
- Onze Lieve Vrouw Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
For this study, a previously developed population pharmacokinetic (popPK) model for cefepime (Jonckheere et al., submitted to JAC) was programmed in Rugloop vII, which is a software program to drive an infusion pump. By entering patient data (such as gender, serum creatinine, age and weight) in Rugloop II, a patient-specific dose will be calculated and given to the patient. This concept is known as Target Controlled Infusion (TCI). The aim of this study is to prospectively validate the popPK model using TCI.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | TCI group | Drug: cefepime, Device: Target Controlled Infusion pump connected to Rugloop vII software |
Timeline
- Start date
- 2016-03-01
- Primary completion
- 2018-03-01
- Completion
- 2019-02-28
- First posted
- 2016-02-23
- Last updated
- 2019-03-01
Source: ClinicalTrials.gov record NCT02688582. Inclusion in this directory is not an endorsement.