NCT02686632

The Effectiveness of Palatal Brushing on Denture Stomatitis

Improving Practice Guidelines for the Treatment of Denture-related Erythematous Stomatitis: A Pragmatic International Multicenter Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 52 (actual)
• Sponsor: Université de Montréal · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Accepted

Summary

Denture stomatitis (DS) is an oral biofilm associated inflammatory disease of the palatal mucosa. It is the most prevalent oral disease and the main indicator of poor oral health among denture wearers, affecting one-third of all complete denture wearers. The etiology of DS is multifactorial, with documented role of mechanical trauma, bacteria and fungi. Risk factors may include, poor oral hygiene and nocturnal use of dentures. However, the evidence is ambiguous, inconclusive and recurrence following routine antifungal therapy is common. The proposed study is a phase II clinical trial to evaluate the efficacy of palatal brushing in reducing the colony forming unit (CFU) count and clinical inflammation. The assessment of change in CFU count and clinical inflammation will be carried out at baseline, 3 months and 6 months.

Conditions

• Denture Stomatitis

Interventions

Type	Name	Description
BEHAVIORAL	Palatal brushing	Brushing the palate as part of regular oral hygiene habits (behavior) among complete denture wearers.

Timeline

• Start date: 2016-09-01
• Primary completion: 2018-05-01
• Completion: 2018-05-01
• First posted: 2016-02-19
• Last updated: 2018-05-02

Locations

1 site across 1 country: Canada