NCT02680678

The Effect of the Timing of Colloid and Crystalloid Infusions on Postspinal Hypotension After Spinal Anesthesia for Caesarian Section

Prevention of Postspinal Hypotension After Spinal Anesthesia for Caesarian Section, the Comparison of Crystalloid and Colloid Infusions and Their Timing Via Perfusion Index and Plethysmographic Variability Index

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Balikesir University · Academic / Other
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Prevention of postspinal hypotension after spinal anesthesia for caesarian section by use of preoperative or intraoperative volume replacement. The comparison of crystalloid and colloid infusions and their timing via perfusion index and plethysmographic variability index.

Detailed description

To Prevent hypotension fluid replacement is usually used in pregnant patients scheduled for C/S. Different types of fluids can be used in order to achieve this. Also the timing of fluid replacement is important. In the present study patients were separated into 4 groups. Each receiving a one of two fluids in different times. ( Colloid pre-load, colloid co-load, crystalloid co-load and crystalloid pre-load.) The effect of overall hemodynamics and the incidence of hypotension are evaluated. Also peripheric monitors like perfusion index and plethysmographic variability index are evaluated for correlation.

Conditions

• Complications; Anesthesia, Spinal and Epidural, in Pregnancy

Interventions

Type	Name	Description
OTHER	Colloid Preload	preload infusion
OTHER	colloid co-load	co-load infusion
OTHER	Crystalloid preload	preload infusion
OTHER	Crystalloid Co-load	co-load infusion

Timeline

• Start date: 2014-04-01
• Primary completion: 2016-08-01
• Completion: 2016-12-01
• First posted: 2016-02-11
• Last updated: 2020-01-22

Locations

1 site across 1 country: Turkey (Türkiye)