Trials / Completed
CompletedNCT02679885
Teriflunomide Male Transmission Study
Assay of Teriflunomide Concentrations in Males Taking Teriflunomide for Treatment of Multiple Sclerosis and Their Female Sexual Partners
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 20 (actual)
- Sponsor
- Griffin Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Not accepted
Summary
It is known that teriflunomide, a treatment for relapsing forms of multiple sclerosis, can be found in low concentrations in semen. Because the drug has been associated with teratogenicity in laboratory animals, the question is raised as to whether the drug can be detected in female partners of sexually active males who are taking the drug to treat their multiple sclerosis.
Detailed description
A total of 10 couples were enrolled in the study. Females partners had undetectable or borderline levels of teriflunomide.
Conditions
Timeline
- Start date
- 2015-10-01
- Primary completion
- 2018-08-01
- Completion
- 2018-09-01
- First posted
- 2016-02-10
- Last updated
- 2019-01-02
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02679885. Inclusion in this directory is not an endorsement.