NCT02679222

Comparing the Ketogenic Effect of Coconut Oil and Different MCTs

Comparing the Ketogenic Effect of Coconut Oil and Different Medium-chain Triglycerides

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Université de Sherbrooke · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to compare the ketogenic effect of coconut oil and three MCT oils (60-40 , tricaprylin and triheptanoate) on the production of ketones in healthy adults. Each oil are evaluated individually or in combination over a 8h-period during which repeated blood sampling is performed.

Detailed description

The study is composed of eight successive visits. Each visit consists of the consumption of one individual oil or a mixture of oils (20 g of coconut oil or 10 g of coconut oil + 10 g of MCT 60-40 or 20 g MCT 60-40 or 10 g coconut oil + 10 g tricaprylin or 20 g tricaprylin or 10 g coconut oil + 10 g triheptanoate or 20 g triheptanoate) and a 8h follow-up during which repeated blood samples are taken for laboratory analysis (plasma beta-hydroxybutyrate, acetoacetate, glucose, free fatty acids, triglycerides, total cholesterol, lactate and insulin).

Conditions

• Healthy Adults

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Coconut oil	20 g of coconut oil
DIETARY_SUPPLEMENT	Coconut oil + MCT	10 g of coconut oil + 10 g of MCT (60 of C8 + 40 of C10)
DIETARY_SUPPLEMENT	MCT	20 g of MCT (60 of C8+40 of C10)
DIETARY_SUPPLEMENT	Coconut oil + tricaprylin	10 g coconut oil + 10 g tricaprylin
DIETARY_SUPPLEMENT	Tricaprylin	20 g tricaprylin
DIETARY_SUPPLEMENT	Tricaprin	20 g tricaprin
DIETARY_SUPPLEMENT	Control	No supplement taken on this visit

Timeline

• Start date: 2015-06-01
• Primary completion: 2016-12-01
• Completion: 2017-03-01
• First posted: 2016-02-10
• Last updated: 2020-04-06
• Results posted: 2020-04-06

Locations

1 site across 1 country: Canada