NCT02679092

Mifepristone Versus Osmotic Dilators in Conjunction With Misoprostol for Cervical Preparation Prior to D&E at 14-19 Weeks

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Stanford University · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Dilation and evacuation (D\&E) is a common surgical procedure in the U.S. Adequate pre-operative preparation of the uterine cervix is an important part of preventing complications of the procedure. Traditionally, the uterine cervix is prepared for the procedure using water-attracting dilators, which are placed via a speculum exam and cause discomfort for many women. The objective of this study is to investigate the comparative effectiveness of mifepristone (an oral tablet) versus dilators for cervical preparation for D\&E.

Conditions

• Legally Induced Abortion Without Mention of Complication

Interventions

Type	Name	Description
DRUG	Misoprostol	400 mcg buccal 60-90 minutes prior to procedure
DRUG	Mifepristone	200 mg PO on the day prior to D\&E
DEVICE	Hygroscopic cervical dilators	osmotic cervical dilators inserted through the internal os

Timeline

• Start date: 2016-04-01
• Primary completion: 2020-02-01
• Completion: 2020-12-01
• First posted: 2016-02-10
• Last updated: 2019-09-19

Locations

1 site across 1 country: United States