NCT02676518

AMH, Glucose Intolerance and Metabolic Syndrome in PCOS

Anti-Müllerian Hormone and Its Association With Glucose Intolerance and Metabolic Syndrome in Women With Polycystic Ovary Syndrome

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 70 (estimated)
• Sponsor: Chulalongkorn University · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

Association between serum anti-Mullerian hormone (AMH) level and prevalence of glucose intolerance and metabolic syndrome in women with polycystic ovary syndrome (PCOS)

Detailed description

* To study the association between serum anti-Mullerian hormone (AMH) level and glucose intolerance and metabolic syndrome in women with polycystic ovary syndrome (PCOS). * Glucose intolerance is detected by 2-hours 75 gram oral glucose tolerance test (OGTT). * Metabolic syndrome is diagnosed by using the Harmonized criteria; the presence of any 3 of 5 following risk factors constitutes a diagnosis of metabolic syndrome. 1. Elevated waist circumference (\> 80 cm in Asian women) 2. Elevated triglycerides (\> 150 mg/dL) 3. Reduced HDL-cholesterol (\< 50 mg/dL) 4. Elevated blood pressure )systolic \> 130 and/or diastolic \> 85 mmHg) 5. Elevated fasting glucose ( \> 100 mg/dL) * Percentage of glucose intolerance and metabolic syndrome in PCOS women as well was any differences in parameters between PCOS patients with and without glucose intolerance and metabolic syndrome will be analysed.

Conditions

• Polycystic Ovary Syndrome

Interventions

Type	Name	Description
OTHER	serum	Serum for serum anti-Mullerian hormone, 2-hour 75 gram oral glucose tolerance test and lipid profiles

Timeline

• Start date: 2015-04-01
• Primary completion: 2016-05-01
• Completion: 2016-05-01
• First posted: 2016-02-08
• Last updated: 2016-02-08

Locations

1 site across 1 country: Thailand