Trials / Completed
CompletedNCT02675686
Amniotic Biomarkers for the Prediction of Postpartum Renal Function.
Amniotic Fluid Biomarker Research for Prediction of Postnatal Renal Function in Fetus With a Bilateral Abnormal Renal Development: National, Multicenter, Prospective and Non-interventional Study.
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 358 (actual)
- Sponsor
- University Hospital, Toulouse · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Accepted
Summary
The discovery of antenatal bilateral renal anomaly poses an essential question: can we predict postnatal renal function? Ultrasound is insufficiently precise to predict postnatal renal function evolution. The objective of this study is to estimate the specificity and sensitivity of amniotic fluid biomarkers to predict postnatal renal function in fetuses with bilateral developmental nephropathies. Both fetuses with bilateral renal anomalies and control (healthy) fetuses will be included. For this study amniotic fluid will only be collected according to routine clinical practice and only excess amniotic fluid sample will be used for the study. The potentially identified biomarkers will not change routine management of the pregnancies in the study.
Conditions
Timeline
- Start date
- 2010-12-01
- Primary completion
- 2016-12-01
- Completion
- 2016-12-01
- First posted
- 2016-02-05
- Last updated
- 2024-11-29
Locations
31 sites across 1 country: France
Source: ClinicalTrials.gov record NCT02675686. Inclusion in this directory is not an endorsement.