Trials / Unknown
UnknownNCT02672306
Safety and Exploratory Efficacy Study of UCMSCs in Patients With Alzheimer's Disease
Clinical Study on the Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Injection in the Treatment of Mild and Moderate Alzheimer's Disease
- Status
- Unknown
- Phase
- Phase 1 / Phase 2
- Study type
- Interventional
- Enrollment
- 16 (estimated)
- Sponsor
- South China Research Center for Stem Cell and Regenerative Medicine · Academic / Other
- Sex
- All
- Age
- 50 Years – 85 Years
- Healthy volunteers
- Not accepted
Summary
The primary purpose of this study is to evaluate the safety and the efficacy of (Human Umbilical Cord-Derived Mesenchymal Stem Cells) UCMSCs for patients with Alzheimer's disease (AD).
Detailed description
Study Type: Interventional Study Design: Treatment, Parallel Assignment, Double Blind (Subject, Outcomes Assessor), Randomized, Safety/ Efficacy Study Official Title: Multicenter, Randomized, Double-blind, Placebo Controlled Trial of UCMSCs in Subjects With Alzheimer's Disease
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | UCMSCs | Biological: Human UCMSCs 20 million cells per subject (0.5×10\^6 UCMSCs per kg) intravenous injection Infusion number: 8 (Once every two weeks) |
| BIOLOGICAL | Placebo | Subjects with Alzheimer's Disease placebo comparator (normal saline) intravenous injection Infusion number: 8 (Once every two weeks) |
Timeline
- Start date
- 2017-10-20
- Primary completion
- 2018-10-01
- Completion
- 2019-10-01
- First posted
- 2016-02-03
- Last updated
- 2018-04-26
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT02672306. Inclusion in this directory is not an endorsement.