NCT02671344

Determining the Genetic Profile in Semen Donors With Pregnancy, Donor Versus no Pregnancy Obtained in TRA

Determination of Gene Profiling in Semen Donors With Pregnancy Versus no Donor Gestation, Obtained in Assisted Reproduction Treatments

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 14 (actual)
• Sponsor: IVI Bilbao · Academic / Other
• Sex: Male
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

Microarray experiments to assess the expression of thousands of genes providing vast amount of information. Because the molecular requirements in the different processes related to playback,on the hypothesis that there may be more apt semen samples for technical or other assuming molecular differences in RNA content messengers or gene expression profile between the They getting semen samples in gestation versus those who do not. In an attempt to give a functional data obtained view, it is to find out how many of these genes in donors who have obtained gestation, they are differentially expressed in playback related processes against those donors who did not get pregnant.

Detailed description

MRNA assembly is characterized by using microarrays on semen samples from donors included in the donation program of the clinic. This process is performed in donors who have generated at least 3 pregnancies compared those samples, however, were not a function of gestation assisted reproduction technique used. Consequently, differential expression of genes are identified in assisted reproduction treatment cycles from IAD, IVF or ICSI.

Conditions

• Donor Site Complication

Interventions

Type	Name	Description
OTHER	Determination of gene profiles using arrays semen	Determination of gene profiles characterizing the set of mRNA and functional interpretation of the resulting list of genes.

Timeline

• Start date: 2015-04-01
• Primary completion: 2016-05-01
• Completion: 2017-12-01
• First posted: 2016-02-02
• Last updated: 2020-02-12

Locations

1 site across 1 country: Spain