NCT02669628

Antimullerian Hormone in Endometriomas

Anti-mullerian Hormone in Ovarian Reserve Evaluation After Treatment of Endometriomas With Alcohol Sclerotherapy Versus Surgery. A Pilot Study.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 34 (actual)
• Sponsor: Hospital Universitari de Bellvitge · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this multicenter study is to evaluate the ovarian reserve after alcohol sclerotherapy of endometriomas versus conventional surgery.

Detailed description

Between 5-10% fertile women are affected by endometriosis, and ovarian endometrioma is present in 17-44% of cases, with 40% of patients with endometriomas being sterile. However, the "gold standard" treatment is laparoscopic ovarian cystectomy and this therapy is associated with a diminished ovarian reserve, with a significant antimullerian hormone (AMH) decrease. Alcohol sclerotherapy is a new minimal invasive procedure in endometrioma treatment whose potential beneficial effect in fertility preservation is not still demonstrated. The investigators would like to demonstrate that this procedure improves fertility preservation and reduces morbidity and costs in contrast with conventional surgery. Moreover,the investigators would like to demonstrate that this procedure could be performed in different centers with similar results.

Conditions

• Endometriomas

Interventions

Type	Name	Description
PROCEDURE	Surgical technique	Laparoscopic surgery
PROCEDURE	Alcohol sclerotherapy	US-guided sclerotherapy

Timeline

• Start date: 2016-02-01
• Primary completion: 2018-01-01
• Completion: 2018-01-01
• First posted: 2016-02-01
• Last updated: 2018-02-23

Locations

1 site across 1 country: Spain