NCT02669186

Effects of Anesthetic Technique on NK Cells

Effects of Anesthetic Technique on Natural Killer Cell Population and Cytotoxicity

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Cedars-Sinai Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The proposed study is a pilot prospective, single-blinded, randomized controlled trial evaluating the effects of two routine, standard-of-care, anesthetic techniques on natural killer cell population size and cytotoxicity in patients undergoing exploratory abdominal laparotomies.

Conditions

• Pain
• Anesthesia
• Cancer

Interventions

Type	Name	Description
DRUG	Bupivacaine + Fentanyl	General endotracheal anesthesia augmented with an epidural. The epidural solution intraoperatively and post-operatively will contain fentanyl + bupivacaine titrated to appropriate surgical conditions and post-operative pain control.
DRUG	Bupivacaine	General endotracheal anesthesia augmented with an epidural. The epidural solution intraoperatively and post-operatively will contain bupivacaine titrated to appropriate surgical conditions and post-operative pain control

Timeline

• Start date: 2019-07-10
• Primary completion: 2025-12-01
• Completion: 2025-12-01
• First posted: 2016-02-01
• Last updated: 2023-08-29

Locations

1 site across 1 country: United States