NCT02668965

The Effects of Intrauterine Infusion of hCG at the Time of Embryo Transfer

The Effects of Intrauterine Infusion of Human Chorionic Gonadotropin at the Time of Embryo Transfer on IVF/ICSI Outcomes: Randomized, Double-blind Controlled Study

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Mahidol University · Academic / Other
• Sex: Female
• Age: 18 Years – 43 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine whether intrauterine hCG can improve the implantation rate and clinical pregnancy rate after embryo transfer in IVF/ICSI cycle.

Detailed description

Patients at infertility clinic, siriraj hospital who come to start IVF/ICSI treatment cycle or endometrial preparation for embryo transfer are consiferes as eligible subjects. On the day of embryo transfer (both fresh and frozen-thaw cycle), the subjects will be randomized to 2 groups. 1. control group: embryo transfer after intrauterine infusion with standard embryo culture media 4-7 minutes 2. study group: embryo transfer after intrauterine infusion with hCG (Pregnyl) 4-7 minutes The patients will come back for serum beta-hCG measurement 2 weeks later after embryo transfer and other 2 weeks later for transvaginal ultrasound if beta-hCG is positive.

Conditions

• Infertility

Interventions

Type	Name	Description
PROCEDURE	Intrauterine hCG (pregnyl)

Timeline

• Start date: 2015-12-01
• Primary completion: 2016-03-01
• Completion: 2016-04-01
• First posted: 2016-01-29
• Last updated: 2016-01-29

Locations

1 site across 1 country: Thailand