Trials / Completed
CompletedNCT02668094
The Effect of Pregabalin on Pain of Propofol Injection
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 120 (actual)
- Sponsor
- Kyungpook National University Hospital · Academic / Other
- Sex
- All
- Age
- 20 Years – 60 Years
- Healthy volunteers
- Not accepted
Summary
Pain is a common side effect of propofol injection. The purpose of this study was to compare the efficacy of pregabalin and lidocaine in reducing propofol injection pain.
Detailed description
In a randomized, double blind, prospective trial, 120 patients were allocated to one of three groups (each n=40) receiving intravenous lidocaine 40mg (group L), oral pregabalin 75 mg (group LP), and oral pregabalin 150 mg (group HP) as pretreatment, followed by injection of 25% of 2 mg/kg propofol. Pain was assessed by a four point scale (0=no, 1=mild, 2=moderate, 3=severe pain).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Lidocaine | |
| DRUG | Pregabalin | |
| DRUG | propofol |
Timeline
- Start date
- 2016-02-01
- Primary completion
- 2016-03-01
- Completion
- 2016-03-01
- First posted
- 2016-01-29
- Last updated
- 2016-05-11
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT02668094. Inclusion in this directory is not an endorsement.