NCT02665260

Safety and Efficacy Study of Topical Cantharidin for the Treatment of Molluscum Contagiosum

Randomized Pilot Study Investigating the Safety and Efficacy of Topical Cantharidin for the Treatment of Molluscum Contagiosum

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 94 (actual)
• Sponsor: Montefiore Medical Center · Academic / Other
• Sex: All
• Age: 2 Years – 17 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine if cantharidin is a safe and effective treatment for molluscum contagiosum in kids

Detailed description

This was a double-blind, placebo-controlled trial. Participants were recruited from the Pediatric Dermatology clinic at Montefiore Medical Center. One hundred eligible participants were randomly assigned to receive cantharidin 0.7% topical, cantharidin 0.7% topical with occlusion, placebo, or placebo with occlusion. Treatments were applied at weeks 0 and 3 (blinded phase). At week 6, all participants were treated with open-label, topical cantharidin 0.7% without occlusion every 3 weeks until all lesions resolved (open-label phase).

Conditions

• Molluscum Contagiosum

Interventions

Type	Name	Description
DRUG	Cantharidin	cantharidin 0.7% topical liquid
DRUG	Placebo	Placebo topical liquid
DEVICE	Gauze occlusion bandage	Gauze occlusion bandage with adhesive tape

Timeline

• Start date: 2012-07-01
• Primary completion: 2015-11-01
• Completion: 2016-01-01
• First posted: 2016-01-27
• Last updated: 2017-05-05
• Results posted: 2017-05-05