Trials / Completed
CompletedNCT02662517
Growth Hormones and Cells in Human Milk Depending on Gestational Age
Growth Hormones and Cells in Human Milk Depending on Gestational Age and Lactation Phase
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 43 (actual)
- Sponsor
- University Hospital of Cologne · Academic / Other
- Sex
- Female
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
Human breast milk contains growth factors including neurotrophins and cells with neuroprotective potential. Concerning growth factors milk of preterms differs significantly from term milk. The aim of this study is to give a profile of human milk concerning non-nutritive factors depending on gestational age and lactation phase.
Detailed description
Neurotrophins (epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), nerve growth factor (NGF), brain derived neurotrophic factor (BDNF)) as well as amount of cells, especially positive for sex-determining transformer protein (TRA)-1-81 and stage-specific embryonic antigen (SSEA)-4, are planned to be quantified in human breast milk of extremely preterm newborns as well as term newborns at different stages of lactation.
Conditions
Timeline
- Start date
- 2016-03-01
- Primary completion
- 2016-09-30
- Completion
- 2017-01-01
- First posted
- 2016-01-25
- Last updated
- 2020-01-18
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT02662517. Inclusion in this directory is not an endorsement.