NCT02658526

Cognitive Changes in Childs After Anesthesia / Surgery

Role of Anesthesia / Surgery on Cognitive Function in Child

• Status: Withdrawn
• Phase: —
• Study type: Observational
• Enrollment: 0 (actual)
• Sponsor: Konstanze Plaschke · Academic / Other
• Sex: All
• Age: 9 Months – 3 Years
• Healthy volunteers: Accepted

Summary

The role of surgical stress and anesthesia is unknown in the early childhood. In vitro and animal studies showed a risk for treatment with anesthesia in the developmental brain. Furthermore, stress is also an important risk factor for cognitive impairment. Therefore, the investigators want to investigate in a clinical prospective cohort study the role anesthesia and surgery on different cognitive parameters and self-controling mechanisms in children under 3 years.

Detailed description

In order to investigate the role of anesthesia and / or surgery on cognitive abilities the investigators want to perform a prospective cohort study in children under 3 years. Three groups should be compared: i) control without anesthesia / surgery, ii) children with only anesthesia, and iii) children with both surgery and anesthesia. All children will be investigate before and after intervention. Different behavioral scales will be used for detailed cognitive abilities and self-regulatory skills.

Conditions

• Behavioral

Interventions

Type	Name	Description
BEHAVIORAL	anesthesia - surgery

Timeline

• Start date: 2015-12-01
• Primary completion: 2020-12-01
• Completion: 2020-12-01
• First posted: 2016-01-20
• Last updated: 2021-04-30

Locations

1 site across 1 country: Germany