NCT02657564

Renal Safety of Bowel Preparation With Polyethylene Glycol

The Renal Safety of Bowel Preparation With Polyethylene Glycol for Colonoscopy: A Prospective Cohort Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,237 (actual)
• Sponsor: Evergreen General Hospital, Taiwan · Academic / Other
• Sex: All
• Age: 40 Years
• Healthy volunteers: Not accepted

Summary

This study evaluates the changes of renal function after taking bowel cleansing agent polyethylene glycol for elective colonoscopy.

Detailed description

Polyethylene glycol (PEG) is the most commonly used bowel cleansing agent for colonoscopy in the world. PEGs are non-absorbable isosmotic solutions that pass through the bowel without net absorption or secretion. Significant fluid and electrolyte shifts are therefore attenuated. However, several studies have shown that PEG may also impair renal function. One recent population-based study reported that the use of PEG was associated with an increased risk of acute kidney injury. The renal safety of PEG in Taiwanese patient has not been reported.

Conditions

• Acute Kidney Injury

Interventions

Type	Name	Description
DRUG	Polyethylene glycol (PEG)	Participants receive blood tests for serum creatinine and electrolytes (Ca, P, Cl, Mg, Na, K) before and after taking polythylene glycol.

Timeline

• Start date: 2016-01-01
• Primary completion: 2017-06-30
• Completion: 2017-06-30
• First posted: 2016-01-18
• Last updated: 2019-02-05
• Results posted: 2019-02-05

Locations

1 site across 1 country: Taiwan