Clinical Trials Directory

Trials / Terminated

TerminatedNCT02656615

Abiraterone-Rechallenge Study for CRPC Patients

An Open Label Biomarker Driven Phase II Clinical Trial of Abiraterone Acetate (AA) Re-Challenge in Patients With Metastatic Castration-Resistant Prostate Cancer and Prior Response to AA

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
4 (actual)
Sponsor
Aurelius Omlin · Academic / Other
Sex
Male
Age
18 Years – 100 Years
Healthy volunteers
Not accepted

Summary

To assess activity of abiraterone-re-challenge in patients with advanced prostate cancer and prior response to abiraterone.

Detailed description

To assess activity of abiraterone-re-challenge in patients with advanced prostate cancer and prior response to abiraterone. CRPC patients with prior response to abiraterone (confirmed PSA Response) and progression can be re-challenged with abiraterone. Patients may have received treatment with docetaxel, enzalutamide and radium-223.

Conditions

Interventions

TypeNameDescription
DRUGabiraterone acetateAbiraterone acetate 1000 mg once daily and Prednisone 2x5 mg daily (continuously as per prescription label).

Timeline

Start date
2016-01-01
Primary completion
2017-02-01
Completion
2017-02-01
First posted
2016-01-15
Last updated
2017-03-24

Locations

3 sites across 1 country: Switzerland

Source: ClinicalTrials.gov record NCT02656615. Inclusion in this directory is not an endorsement.