NCT02655783

Use of Normal Saline With or Without Dextrose During Induction of Labor in Nulliparous

Utilisation parentérale de Normal Salin Avec ou Sans Dextrose Durant l'Induction du Travail Chez Les Nullipares

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (actual)
• Sponsor: Université de Sherbrooke · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The objective of this study is to compare the effects of use of normal saline (250 cc / h), with or without dextrose supplement, on the evolution of labor in nulliparous.

Detailed description

There is some controversy regarding intravenous hydration of patients during labor. While the use of a fast flow of hydration appears to be recognized beneficial, the addition of glucose is less well accepted. However studies on exercise physiology clearly demonstrates improved performance of skeletal muscle by increased hydration and carbohydrate replacement during prolonged exercise. This situation is similar to the condition of the uterus in labor especially since it is now established that glucose represents its principal source of energy. However, the effect of an additional carbohydrate intake on the evolution of labor has not been extensively studied until now, and there are several schools of thought on this subject. While some studies show that such glucose addition could reduce the total duration of labor as well as its second stage, others claim that this glucose supplement offers no benefit and may even be harmful to the fetus. It therefore seems imperative to conduct a study to compare the use of hydration with normal saline with or without dextrose during labor, as recommended in current flow (250 cc / h). To our knowledge, this has never been done.

Conditions

• Delivery Uterine

Interventions

Type	Name	Description
OTHER	5% dextrose	women with an elective induction of labor receive IV hydratation (250 ml/h) with a normal saline solution + 5% dextrose
OTHER	normal saline	women with an elective induction of labor receive IV hydratation (250 ml/h) with a normal saline solution

Timeline

• Start date: 2013-01-01
• Primary completion: 2016-03-01
• Completion: 2016-09-01
• First posted: 2016-01-14
• Last updated: 2016-10-31

Locations

1 site across 1 country: Canada