NCT02654496

Gut Microbiota Post Roux-en-Y Gastric Bypass Surgery

The Gut Microbiota in Patients Post Roux-en-Y Gastric Bypass Surgery

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 19 (actual)
• Sponsor: North Dakota State University · Academic / Other
• Sex: Female
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to investigate mechanisms responsible for weight change in patients who have undergone weight loss surgery. Specifically, we will compare the gut microbiota, plasma bile acids, plasma gut peptides (GLP-1, GLP-2, and PYY), and plasma LPS in three groups of subjects: 3-5 years post gastric bypass patients who experienced sub-optimal weight loss, 3-5 years post gastric bypass patients who had successful weight loss, and a control group who has not had a weight loss surgery and are of similar age, gender, body mass index as the gastric bypass groups.

Conditions

• Obesity

Interventions

Type	Name	Description
OTHER	Meal challenge	Participants will receive a liquid nutritional supplement. Before and after administration, biological variables of interest will be collected.

Timeline

• Start date: 2016-01-01
• Primary completion: 2017-09-01
• Completion: 2017-12-01
• First posted: 2016-01-13
• Last updated: 2018-08-23

Locations

1 site across 1 country: United States