Trials / Completed
CompletedNCT02654236
Effect of Heavy Alcohol Consumption on Farnesoid X Receptor (FXR) Signaling
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 30 (actual)
- Sponsor
- Suthat Liangpunsakul · Academic / Other
- Sex
- All
- Age
- 21 Years – 65 Years
- Healthy volunteers
- Accepted
Summary
The main purpose of this study is to see whether heavy drinking will interfere with a specific pathway, called FXR signaling in the liver. The abnormality of this pathway may lead to liver injury in some patients who drink heavily.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Placebo | 1 tablet of placebo, taken orally daily with water, approximately 30 minutes prior to breakfast for 4 weeks. |
| DRUG | 10 mg Obeticholic Acid (OCA) | 10 mg Obeticholic Acid (OCA) Study medication will be administered orally, once daily, approximately 30 minutes prior to breakfast for 4 weeks. |
Timeline
- Start date
- 2016-04-01
- Primary completion
- 2019-09-01
- Completion
- 2019-09-01
- First posted
- 2016-01-13
- Last updated
- 2023-04-25
- Results posted
- 2023-04-25
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02654236. Inclusion in this directory is not an endorsement.