NCT02651636

Combined Therapy With Myo-inositol and Alpha-Lipoic Acid in PCOS Women

Effects of Combined Therapy With Myo-inositol and Alpha-Lipoic Acid on Clinical, Endocrine and Metabolic Features in Women Affected by Polycystic Ovary Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Catholic University of the Sacred Heart · Academic / Other
• Sex: Female
• Age: 18 Years – 35 Years
• Healthy volunteers: Not accepted

Summary

The aim of our study is to investigate the effects of a combined treatment of alpha-lipoic acid and myoinositol on clinical, endocrine and metabolic features of women affected by PCOS. The study Group included 40 patients treated with a combined therapy of alpha-lipoic acid (800 mg), myoinositol (2000 mg) and folic acid (400 mcg) daily for six months. The investigation includes menstrual pattern, hirsutism score, hormonal assays, oral glucose tolerance test, lipidic profile at baseline and after six months of treatment.

Conditions

• Polycystic Ovary Syndrome
• Menstrual Pattern
• Hyperandrogenism
• Metabolic Features

Interventions

Type	Name	Description
DRUG	myo-inositol,alpha-lipoic acid and folic acid

Timeline

• Start date: 2014-06-01
• Primary completion: 2015-07-01
• First posted: 2016-01-11
• Last updated: 2016-01-11