NCT02651467

A Study to Investigate Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Pain Derived From Exposed Dentine in Response to Chemical, Thermal, Tactile, or Osmotic Stimuli.

A Clinical Study Investigating the Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Dentinal Hypersensitivity

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 221 (actual)
• Sponsor: GlaxoSmithKline · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This will be a single center, eight week, randomized, double blind, three treatment arm, parallel design, stratified (by mean baseline Schiff Sensitivity Score of the two selected test teeth) study in healthy participants.

Conditions

• Dentin Sensitivity

Interventions

Type	Name	Description
OTHER	Experimental Oral Rinse 1 (1.5% w/w KOX, 0ppm F, pH 7.0)	1.5% w/w KOX, 0ppm F, pH 7.0
OTHER	Experimental Oral Rinse 2 (2.0% w/w KOX, 45ppm F, pH 4.5)	2.0% w/w KOX, 45ppm F, pH 4.5
OTHER	Placebo Oral Rinse (0% w/w KOX 0ppm F, pH 4.5 )	0% w/w KOX 0ppm F, pH 4.5

Timeline

• Start date: 2016-01-04
• Primary completion: 2016-04-01
• Completion: 2016-04-22
• First posted: 2016-01-11
• Last updated: 2018-08-27
• Results posted: 2017-03-09

Locations

1 site across 1 country: United States