Trials / Completed
CompletedNCT02649712
Unilateral Stenting Versus Bilateral Stenting for Malignant Hilar Biliary Obstruction
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 72 (actual)
- Sponsor
- Xuzhou Central Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 85 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to compare the clinical effectiveness and long-term outcomes between patients with malignant hilar biliary obstruction who are treated by unilateral or bilateral stenting.
Detailed description
Malignant hilar biliary obstruction is a common clinical manifestation and it can be caused by cholangiocarcinoma, gallbladder carcinoma, liver cancer, or other metastatic carcinoma. Most patients with malignant hilar biliary obstruction are unresectable at diagnosis. Biliary stenting has been widely used in palliative treatment of malignant hilar biliary obstruction. Hilar biliary obstruction usually involves the bifurcation of the biliary tract. Some researchers recommended unilateral stenting for malignant hilar biliary obstruction because drainage of 25% of entire liver can achieve the clinical success of biliary drainage. However, some researchers recommended bilateral stenting for malignant hilar biliary obstruction because some researches demonstrated that bilateral stenting can achieve a longer stent patency.In addition, there was no significant difference in post stenting survival between patients who were treated by unilateral or bilateral stenting. Therefore, it remains under debate whether unilateral or bilateral stenting is better in the treatment of malignant hilar biliary obstruction. The purpose of this study is to compare the clinical effectiveness and long-term outcomes between patients with malignant hilar biliary obstruction who are treated by unilateral or bilateral stenting.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | biliary stent | Self-expandable biliary nitinol alloys stent |
Timeline
- Start date
- 2016-01-20
- Primary completion
- 2018-10-31
- Completion
- 2018-10-31
- First posted
- 2016-01-07
- Last updated
- 2018-11-20
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT02649712. Inclusion in this directory is not an endorsement.