Clinical Trials Directory

Trials / Completed

CompletedNCT02648295

Effects of IV Tranexamic Acid on the Thromboelastogram in Patients Undergoing Total Hip or Knee Arthroplasty

Status
Completed
Phase
Study type
Observational
Enrollment
60 (actual)
Sponsor
West Virginia University · Academic / Other
Sex
All
Age
40 Years – 90 Years
Healthy volunteers
Accepted

Summary

Blood management is an important part of successful total joint replacement. Loss of blood and transfusion can lead to poor outcomes for patients. The use of tranexamic acid (TXA) has become a standard component to many blood management programs. It is used to treat or prevent excessive blood loss during surgery and in various medical conditions such as excessive bleeding or hemorrhage. A normal body process prevents blood clots that occur naturally from growing and causing problems. When this process becomes overactive it can result in excessive bleeding, leading to increased blood transfusions. The proposed study seeks to evaluate the relationship between TXA and thromboelastogram (TEG) results.

Conditions

Interventions

TypeNameDescription
PROCEDUREEffects of IV TXA on TEG in patients undergoing THA or TKASubjects will undergo surgery per standard of care. All subjects will have 3 additional vials of blood drawn to evaluate TEG.

Timeline

Start date
2015-12-01
Primary completion
2016-10-01
Completion
2016-10-01
First posted
2016-01-07
Last updated
2017-10-26

Source: ClinicalTrials.gov record NCT02648295. Inclusion in this directory is not an endorsement.