Trials / Terminated
TerminatedNCT02644083
Tecfidera and MRI for Brain Energy in MS
Modulation of Cerebral Grey Matter High Energy Phosphate Metabolites in Multiple Sclerosis by Dimethyl Fumarate
- Status
- Terminated
- Phase
- —
- Study type
- Observational
- Enrollment
- 4 (actual)
- Sponsor
- Oregon Health and Science University · Academic / Other
- Sex
- All
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Not accepted
Summary
The primary objective of this study is to test the hypothesis that DMF can improve mitochondrial function in the brain of people with MS. The investigators will assess mitochondrial function in the cerebral grey matter by measuring PCr and ATP by 31P magnetic resonance spectroscopy (MRS) and NAA in NAWM by 1H MRS.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Dimethyl fumarate |
Timeline
- Start date
- 2016-02-01
- Primary completion
- 2018-07-01
- Completion
- 2018-07-01
- First posted
- 2015-12-31
- Last updated
- 2018-08-29
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02644083. Inclusion in this directory is not an endorsement.