NCT02642861

Cyclobenzaprine in Muscle Cramps With Liver Cirrhosis

Cyclobenzaprine Treatment for Muscle Cramps in Cirrhotic Patients

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

\- Cyclobenzaprine, is a muscle relaxer medication used to relieve skeletal muscle spasms. It is one of the best-studied drug for this application.

Detailed description

Although a number of mechanisms for cramps in liver disease have been postulated and have been targeted by medical therapies, a clear picture of the causal events has not emerged. Several agents as vitamin E, human albumin, zinc, taurine, eperisone hydrochloride and branched-chain amino acids have shown some benefit in small uncontrolled studies, although large randomized controlled trials are lacking. \- Cyclobenzaprine, is a muscle relaxer medication used to relieve skeletal muscle spasms. It is one of the best-studied drug for this application.

Conditions

• Liver Cirrhosis

Interventions

Type	Name	Description
DRUG	Cyclobenzaprine	cyclobenzaprine administration for 2 weeks
DRUG	Calcium Carbonate	Calcium carbonate for 2 weeks

Timeline

• Start date: 2018-10-01
• Primary completion: 2019-12-01
• Completion: 2019-12-01
• First posted: 2015-12-30
• Last updated: 2018-01-03

Locations

1 site across 1 country: Egypt