Clinical Trials Directory

Trials / Completed

CompletedNCT02640625

Improving Prognosis in HIV Infection

Adjuvant Mucosal Therapy in HIV-infected Men With Insufficient Response to Antiretroviral Therapy

Status
Completed
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
20 (actual)
Sponsor
Oslo University Hospital · Academic / Other
Sex
Male
Age
25 Years – 65 Years
Healthy volunteers
Accepted

Summary

The primary objective of this study is to assess the safety of probiotics in cART-treated immunologic non-responder (INR) patients with chronic HIV infection. The secondary objectives are to i) explore the biological effects of probiotics in combined antiretroviral therapy(cART)-treated INR patient with chronic HIV infection, and ii) investigate differences between cART-treated HIV-infected INR and non-INR patients with regards to gut microbial composition and mucosal barrier function.

Conditions

Interventions

TypeNameDescription
DIETARY_SUPPLEMENTProbiotic compoundLactobacillus rhamnosus GG, Lactobacillus acidophilus, Lactobacillus bulgaricus, Bifidobacterium animalis subsp. lactis, and Streptococcus thermophilus.

Timeline

Start date
2016-01-01
Primary completion
2017-03-01
Completion
2017-04-01
First posted
2015-12-29
Last updated
2021-12-06
Results posted
2020-03-27

Locations

1 site across 1 country: Norway

Source: ClinicalTrials.gov record NCT02640625. Inclusion in this directory is not an endorsement.