Trials / Completed
CompletedNCT02638181
The Expression of Matrix Metalloproteinase 13, Tissue Inhibitor of Metalloproteinases 3, and Calcium-sensing Receptor in Human Trabecular Meshwork
The Expression of Matrix Metalloproteinase 13（MMP13）, Tissue Inhibitor of Metalloproteinases 3（TIMP13）, and Calcium-sensing Receptor（CaSR） in Human Trabecular Meshwork
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 60 (actual)
- Sponsor
- Lv Yingjuan · Academic / Other
- Sex
- All
- Age
- 50 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
This study was to assess the distinct expression of matrix metalloproteinase 13,tissue inhibitor of metalloproteinases 3, and calcium-sensing receptor, in human trabecular meshwork between normal and glaucomatous eyes.The expressions of matrix metalloproteinase 13, tissue inhibitor of metalloproteinases 3 and calcium-sensing receptor in the trabecular meshwork tissues were examined by streptavidin-peroxidase immunohistochemical staining method and western blot, and histological changes of trabecular meshwork were studied by Hematoxylin and Eosin staining.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | trabeculectomy |
Timeline
- Start date
- 2013-07-01
- Primary completion
- 2015-12-01
- Completion
- 2015-12-01
- First posted
- 2015-12-23
- Last updated
- 2017-01-10
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT02638181. Inclusion in this directory is not an endorsement.