NCT02637102

The UK CAVIAR Study

The UK CArdiac and Vascular Surgery Interventional Anaemia Response Study: An Observational Cohort Study to Determine the Impact and Effect of Anaemia in Patients Awaiting Vascular and Cardiac Surgery

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 425 (actual)
• Sponsor: University College, London · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

CAVIAR is a multicentre prospective observational study. Centres for cardiac and vascular surgery assess and manage patients in different ways before surgery. Some centres have introduced the use of intravenous iron therapy for patients with anaemia in the preoperative setting. Consequently regional variation exists in the assessment and management of patients before cardiac and vascular surgery. We aim to observe and measure these differing pathways and observe if there is variation in iron deficiency and anaemia and the impact of these variables on patient cardiorespiratory function as well as post-operative outcomes. \[Sub-Study\] For patients who are receiving intravenous iron therapy as part of their routine clinical care, we wish to observe this effect in more detail. We will assess the impact of the treatment on well-being, blood count and fitness. Information will be collected through Quality of Life questionnaires, total haemoglobin mass test (via blood collection) and fitness testing.

Conditions

• Iron Deficiency
• Cardiac Patients
• Anaemia
• Vascular Patients

Interventions

Type	Name	Description
OTHER	Not applicable - observational study

Timeline

• Start date: 2015-11-01
• Primary completion: 2018-03-01
• Completion: 2019-04-01
• First posted: 2015-12-22
• Last updated: 2023-05-16