Clinical Trials Directory

Trials / Completed

CompletedNCT02635776

Peanut Allergy Oral Immunotherapy Study of AR101 for Desensitization in Children and Adults (PALISADE)

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
555 (actual)
Sponsor
Aimmune Therapeutics, Inc. · Industry
Sex
All
Age
4 Years – 55 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to demonstrate the efficacy and safety of AR101 through reduction in clinical reactivity to peanut allergen in peanut-allergic children and adults.

Detailed description

This is an international, multicenter, randomized, double-blind, placebo-controlled study of the efficacy and safety of AR101 in a characterized desensitization oral immunotherapy regimen in peanut-allergic individuals.

Conditions

Interventions

TypeNameDescription
BIOLOGICALAR101 powder provided in capsules & sachetsStudy product formulated to contain peanut protein at different dosage strengths for use as defined in the protocol
BIOLOGICALPlacebo powder provided in capsules & sachetsStudy product formulated to contain only inactive ingredients for use as defined in the protocol

Timeline

Start date
2015-12-22
Primary completion
2017-12-21
Completion
2018-07-02
First posted
2015-12-21
Last updated
2022-03-17
Results posted
2022-03-17

Locations

69 sites across 10 countries: United States, Canada, Denmark, Germany, Ireland, Italy, Netherlands, Spain, Sweden, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT02635776. Inclusion in this directory is not an endorsement.

Peanut Allergy Oral Immunotherapy Study of AR101 for Desensitization in Children and Adults (PALISADE) (NCT02635776) · Clinical Trials Directory