NCT02633514

Adjuvant Treatment for Incomplete Resection Thymoma or Thymic Carcinoma

A Randomized Phase III Study of Adjuvant Radiotherapy Versus Adjuvant Radiochemotherapy in Patients With Incomplete ResectionThymoma or Thymic Carcinoma

• Status: Recruiting
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 1 (estimated)
• Sponsor: Fudan University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This study is designed to investigate whether adjuvant radiochemotherapy after incomplete resection has a better survival than adjuvant radiotherapy for thymoma or thymic carcinoma.

Detailed description

The previous trials have showed that radiotherapy was significantly associated with prolonged OS and chemotherapy is playing an increasing role in treatment of patients with thymoma or thymic carcinoma.However,whether patients with thymoma or thymic carcinoma could benefit from adjuvant radiochemotherapy after incomplete resection remains controversial. The purpose of this study is to investigate whether adjuvant radiochemotherapy after incomplete resection can improve survival for thymoma or thymic carcinoma.

Conditions

• Thymoma and Thymic Carcinoma

Interventions

Type	Name	Description
DRUG	Cisplatin	25mg/m2,iv gtt,d1-3
DRUG	Etoposide	75mg/m2,iv gtt,d1-3
RADIATION	radiotherapy	60Gy/30Fx

Timeline

• Start date: 2023-12-01
• Primary completion: 2024-12-01
• Completion: 2026-12-01
• First posted: 2015-12-17
• Last updated: 2023-12-05

Locations

1 site across 1 country: China