NCT02631967

Surgical Prevention of Anastomotic Recurrence by Excluding Mesentery in Crohn's Disease

A New Anastomotic Technique After Ileocecal Resection for Crohn's Disease. Kono-s Anastomosis vs Stapled Side-to-side Anastomosis: a Randomized Controlled Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 132 (estimated)
• Sponsor: Federico II University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Kono and collegues have described a new anastomotic technique to restore bowel contintuity after ileocecal resection for Crohn's disease (CD). This tecnique implies a hand-sewn ileocolic anastomosis, that involves exclusively the antimesenteric side of the bowel and that functionally acts as an end-to-end anastomosis. In a retrospective study, the authors have shown that this anastomotic tecnique, when compared to stapled side-to-side anastomosis, significantly reduces the severity of endoscopic recurrence at 1 year after surgery and the rate of reoperation for anastomotic recurrence at 5 years after surgery. Aim of this trial is to compare the outcomes of the Kono anastomosis with the ones achieved by the stapled side-to-side anastomosis, within a prospective randomized study.

Conditions

• Crohn Disease

Interventions

Type	Name	Description
PROCEDURE	Kono anastomosis	Kono anastomosis
PROCEDURE	Stapled side-to-side anastomosis	Stapled side-to-side anastomosis

Timeline

• Start date: 2015-11-01
• Primary completion: 2017-11-01
• Completion: 2022-11-01
• First posted: 2015-12-16
• Last updated: 2017-02-15

Locations

1 site across 1 country: Italy