NCT02630017

Motivated Behavior in Adults With and Without ADHD

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 51 (actual)
• Sponsor: University of Arkansas · Academic / Other
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

To investigate the effects of methylphenidate on motivated behavior in adults with and without ADHD

Detailed description

This study has a mixed between- and within-subject design. Participants are young adults (aged 18-45) with ADHD and non-ADHD matched controls. They will be recruited from locations around the community, consented, screened for eligibility, then scheduled for 2 study days. Study days will be at least 48 hours apart. Thus, there will be a total of 3 lab visits across a 3 week period. Participants will be administered study drug on one study day and placebo on the other study day. They will complete a battery of cognitive/behavioral tasks and answer questionnaires on both study days.

Conditions

• ADHD

Interventions

Type	Name	Description
DRUG	ADHD methylphenidate first, placebo second	double-blind, counter-balanced administration
DRUG	ADHD placebo first, methylphenidate second	double-blind, counter-balanced administration
DRUG	Non-ADHD methylphenidate first, placebo second	double-blind, counter-balanced administration
DRUG	Non-ADHD placebo first, methylphenidate second

Timeline

• Start date: 2016-03-07
• Primary completion: 2018-09-21
• Completion: 2018-09-21
• First posted: 2015-12-15
• Last updated: 2021-08-27
• Results posted: 2021-08-27

Locations

2 sites across 1 country: United States

Regulatory

• FDA-regulated drug study