NCT02627391

Early Surgery for Patients With Asymptomatic Aortic Stenosis

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 360 (estimated)
• Sponsor: Assistance Publique - Hôpitaux de Paris · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Many cardiologists are convinced that early surgery in asymptomatic aortic stenosis (AS) saves lives. However there is currently no direct evidence for this and most recommendations from the ESC/ EACTS or ACC/ AHA in this field are supported by Level-B or C evidence. Therefore, the investigators designed a randomized controlled trial to demonstrate whether early surgery improves mortality and morbidity of patients with asymptomatic severe AS and low operative risk.

Conditions

• Aortic Valve Stenosis
• Aortic Valve Surgery

Interventions

Type	Name	Description
OTHER	Early surgical aortic valve replacement
OTHER	Delayed Surgical aortic valve replacement

Timeline

• Start date: 2016-01-01
• Primary completion: 2018-11-01
• Completion: 2019-11-01
• First posted: 2015-12-10
• Last updated: 2017-07-05

Locations

1 site across 1 country: France