NCT02626533

Persistent Postoperative Pain and Joint Stiffness After Total Knee Arthroplasty Performed for Osteoarthritis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 179 (actual)
• Sponsor: Hospital for Special Surgery, New York · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Persistent pain and joint stiffness after surgery may interfere with recovery and adversely affect quality of life in up to 40% of patients who have undergone total knee arthroplasty. There is growing evidence that inflammation as well as other medical and psychological factors may be associated with osteoarthritis severity, progression, and associated pain severity. This study aims to identify clinical, biological, and psychological factors that contribute to and predict the development of these complications. Identification of such factors may allow us to target preventative measures to the patients at highest risk of persistent postoperative pain and joint stiffness.

Conditions

• Pain
• Joint Stiffness

Interventions

Type	Name	Description
PROCEDURE	Total Knee Arthroplasty	Patients will undergo total unilateral knee arthroplasty for osteoarthritis.

Timeline

• Start date: 2015-12-01
• Primary completion: 2017-08-28
• Completion: 2018-02-28
• First posted: 2015-12-10
• Last updated: 2024-12-27
• Results posted: 2024-07-19

Locations

1 site across 1 country: United States