NCT02620124

GnRH Agonist as Luteal Support in FET Cycles

GnRH Anonist as Luteal Support in Frozen-thawed Embryo Transfer Cycles

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Turku University Hospital · Other Government
• Sex: Female
• Age: 20 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

Back ground: A single dose of GnRH analogue in the luteal phase is reported to improve the outcome of IVF/ICSI treatments but the effect in FET cycles has not been reported. Aim: To compare the results of frozen thawed embryo transfers with and without GnRHa analogue support Primary end point: IR, PR, on going PR Secondary end point: hCH, E2 and progesterone levels 14 days after thawing

Conditions

• Infertility

Interventions

Type	Name	Description
DRUG	Natural cycle: Triptorelin acetate 0.1 mg	A single dose of triptorelin acetate 0.1 s.c. was giwen when the age of the transferred embryo was six days in additon to standard micronized progesterone 400 mg vaginally
DRUG	Hormone replacement cycle and triptorelin acetate 0.1 mg	A single dose of triptorelin acetate 0.1 s.c. was giwen when the age of the transferred embryo was six days in addition to standard Estradiol and progesterone support

Timeline

• Start date: 2013-05-01
• Primary completion: 2015-04-01
• Completion: 2015-10-01
• First posted: 2015-12-02
• Last updated: 2016-11-23