NCT02619188

Nutritional Markers in Normal and Hyperemesis Pregnancies

Pregnancy Unique Questionnaire of Emesis (PUQE) Methode Evaluation; Relation Between Rate of Nausea/Vomiting in Pregnancy (PUQE-score), Self-reported Nutritional Intake and Biochemical Nutritional Markers

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 60 (estimated)
• Sponsor: Haukeland University Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

This study evaluate the rate of nausea and nutritional status in patients with hyperemesis gravidarum (severe nausea and vomiting in pregnancy) and healthy pregnant women using a questionnaire (PUQE-score), self-reported food/drink intake form and blood test. The Investigators aim for developing normal range of prealbumin measurements (reference values) during first trimester of pregnancy.

Detailed description

Women affected with hyperemesis gravidarum are at severe nutritional risk. Reference values for biochemical parameters evaluating nutritional status during early pregnancy needs to be determined. The investigators will compare clinical nutritional parameters (weight gain/weight loss) with rate of nausea (PUQE-questionnaire), self-reported nutritional intake form and biochemical measurements (prealbumin) in women admitted to hospital with hyperemesis gravidarum and healthy pregnant women. For hyperemesis patients measurements will be repeated at discharge.

Conditions

• Hyperemesis Gravidarum
• Pregnancy

Interventions

Type	Name	Description
OTHER	PUQE-form inclusion	PUQE-form encompassing last 24 hours completion
OTHER	Nutritional form inclusion	Food-list form encompassing last 24 hours completion
OTHER	Blood sampling inclusion	Measurement of biochemical nutrition marker(s); Prealbumin
OTHER	Intervention at discharge	PUQE-form, nutritional form and Blood sampling

Timeline

• Start date: 2015-09-01
• Primary completion: 2017-05-01
• Completion: 2018-07-01
• First posted: 2015-12-02
• Last updated: 2016-10-05

Locations

1 site across 1 country: Norway