NCT02618213

Comparison of High Flow Oxygenation Therapy and CPAP in Children With Bronchiolitis.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Esbjerg Hospital - University Hospital of Southern Denmark · Academic / Other
• Sex: All
• Age: 1 Day – 24 Months
• Healthy volunteers: Not accepted

Summary

Bronchiolitis in infants and young children often requires respiraty support. In Denmark Continous Positive Airway Pressure ( CPAP) are routinely used in children with moderate-severe bronchiolitis. The aim of the study is to compare CPAP and High Flow Oxygenation Therapy (HFOT) as tools of respiratory support in infants and young children with bronchiolitis. Infants and young children with moderate-severe bronchiolitis and are randomized to either CPAP or HFOT.

Conditions

• Respiratory Syncytial Virus Bronchiolitis

Interventions

Type	Name	Description
DEVICE	Optiflow Junior	Humified air are dispensed through the system. Airflow, FiO2 (Fraction of inspired oxygen) , SpO2 (peripheral capillary Oxygen saturation) and respiratory rate are noted each hour. Progression of condition might lead to change of system og mechanical ventilation. poor tolerance might lead to change of system
DEVICE	Continous Positive Airway Pressure	Humified air are dispensed throug the system. Airflow, FiO2, SpO2 and respiratory rate are noted each hour. Progression of condition might lead to change of system or mechanical ventilation. Poor tolerance might lead to change of system.

Timeline

• Start date: 2015-12-01
• Primary completion: 2018-05-01
• Completion: 2018-05-01
• First posted: 2015-12-01
• Last updated: 2022-10-25

Locations

2 sites across 1 country: Denmark