NCT02617498

Spray Diathermy Versus Harmonic Scalpel Technique for Hepatic Parenchymal Transection

Spray Diathermy Versus Harmonic Scalpel Technique for Hepatic Parenchymal Transection of Living Donor.

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Mansoura University · Academic / Other
• Sex: All
• Age: 10 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

Consecutive patients, who were treated for end stage liver cirrhosis by LDLT were included in this a prospective study.Patients enrolled in the study divided into two groups according to the day of surgery. The study population was divided into two groups; group (A) Parenchymal liver transection was performed by harmonic scalpel (HS) and group (B) Parenchymal liver transection was performed by spray diathermy (SD).

Detailed description

Consecutive patients, who were treated for end stage liver cirrhosis by LDLT were included in this a prospective study.Patients enrolled in the study divided into two groups according to the day of surgery. The study population was divided into two groups; group (A) Parenchymal liver transection was performed by harmonic scalpel (HS) and group (B) Parenchymal liver transection was performed by spray diathermy (SD). Donors and recipient were followed up after hospital discharge with laboratory investigation, abdominal ultrasound, MRCP in selected cases every month for the first month, then every 6 months and then every year postoperatively. Follow up visits included clinical examination, laboratory investigation, doses of immunosuppressive, radiological examination, and doppler US. The primary outcome was the amount of blood loss during transection. Secondary outcomes were operative time, time of transection, speed of transection/minutes , number of ligation used, degree of postoperative injury which assessed by daily liver function, WBC, C reactive protein, pathological changes at the cut surface, postoperative morbidity (including biliary leakage, collection), cost and hospital stay.

Conditions

• End Stage Liver Disease

Interventions

Type	Name	Description
DEVICE	harmonic scalpel	parenchymal liver transection was performed either by harmonic scalpel after demarcation of line of transection by intraoperative US and doppler.
DEVICE	spray mode diathermy	parenchymal liver transection was performed either by spray mode diathermy after demarcation of line of transection by intraoperative US and doppler.

Timeline

• Start date: 2013-04-01
• Primary completion: 2015-04-01
• Completion: 2015-11-01
• First posted: 2015-12-01
• Last updated: 2016-03-22