NCT02616887

Study of Image-Guided SBRT for Vertebral Metastases

Phase II Study of Image-Guided Single Fraction SBRT With VMAT-FFF Technique for Vertebral Metastases

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 26 (actual)
• Sponsor: Istituto Clinico Humanitas · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Based on the known efficacy of ablative single dose SBRT and VMAT technique in various solid tumors, investigators have designed this study to assess feasibility of SBRT in selected patients with spine metastases.

Detailed description

This is a prospective, phase 2 study. The main objectives are to assess acute and late side effects of single fraction SBRT for selected patients with vertebral metastases and to study the local control of disease in treated sites. The schedule will be 1 fraction of 18 Gy delivered in one day with Volumetric Modulated Arc Therapy (VMAT) and Flattening filter-free (FFF) beams.

Conditions

• Vertebral Metastases

Interventions

Type	Name	Description
RADIATION	Single dose SBRT and VMAT technique	One fraction of 18 Gy delivered in one day with VMAT and Flattening filter-free (FFF) beams.

Timeline

• Start date: 2015-11-05
• Primary completion: 2022-02-08
• Completion: 2022-02-08
• First posted: 2015-11-30
• Last updated: 2022-05-09

Locations

1 site across 1 country: Italy