Trials / Completed
CompletedNCT02615912
A Single-Center, Exploratory Study to Analyze the Dynamics of Skin Microflora Following Exposure to Surfactants
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 24 (actual)
- Sponsor
- Kimberly-Clark Corporation · Industry
- Sex
- All
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to understand the changes in skin microflora, skin barrier function, and skin biochemical constituents in response to direct contact with model surfactants used in personal care articles. The results from this study will provide insights into the complex interaction between the skin microbiome and the epidermis after exposure to surfactants.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | PEG-40 Hydrogenated Castor Oil (Tagat CH40, Evonik) 1.5% | |
| OTHER | Lauryl glucoside (Plantacare® 1200UP, BASF) 1.5% | |
| OTHER | Sorbitan palmitate (SPANTM 40 (powder), Croda) 1.5% | |
| OTHER | Silwet* DA-63 (Momentive) 1.5% | |
| OTHER | Sodium lauryl sulfate (Sigma Aldrich) 1.0% | |
| OTHER | Water (control) |
Timeline
- Start date
- 2015-11-01
- Primary completion
- 2015-12-01
- Completion
- 2016-02-01
- First posted
- 2015-11-26
- Last updated
- 2016-09-28
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02615912. Inclusion in this directory is not an endorsement.