NCT02615223

Endocrine Therapy With or Without Cryoablation for Stage IV Prostate Cancer

A Prospective Multi-center Study to Compare the QOL and Efficacy of Endocrine Therapy With or Without Cryoablation for Stage IV Prostate Cancer.

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: Tianjin Medical University Cancer Institute and Hospital · Academic / Other
• Sex: Male
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This trial is going to evaluate tumor control and quality of life in patients with prostate cancer treated with endocrine therapy with or without cryoablation.

Detailed description

OBJECTIVES: * To determine the tumor control in patients with prostate cancer treated with radiotherapy or cryoablation * To determine the quality of life of these patients. OUTLINE: This is a multicenter study. Patients are stratified according to Gleason score (≥ 8 vs 7 vs ≤ 6), persistent prostatic specific antigen (PSA) at allocation (\> 0.5 ng/mL vs ≤ 0.5 ng/mL), participating center. Patient are allocated to two treatment arms.

Conditions

• Stage IV Prostate Cancer

Interventions

Type	Name	Description
PROCEDURE	cryoablation	Cryoablation therapy
DRUG	Bicalutamide	bicalutamide
DRUG	luteinizing-hormone releasing-hormone (LHRH) agonist	luteinizing-hormone releasing-hormone (LHRH) agonist

Timeline

• Start date: 2015-11-01
• Primary completion: 2017-12-01
• Completion: 2018-12-01
• First posted: 2015-11-26
• Last updated: 2017-06-12

Locations

1 site across 1 country: China