NCT02609802

The Different Analgesic Potency of Volatile Anesthetics at Equi-MAC

The Different Analgesic Potency of Sevoflurane and Desflurane at Equi-minimum Alveolar Concentration

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 77 (actual)
• Sponsor: Kangbuk Samsung Hospital · Academic / Other
• Sex: All
• Age: 19 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The aim of this clinical trial is to evaluate the difference of analgesic potency of sevoflurane and desflurane at equi-minimum alveolar concentration using a surgical pleth index.

Detailed description

Volatile anesthetics vary in their relative hypnotic potencies. Recent studies demonstrated that equi-minimum alveolar concentration of various volatile anesthetics produced different EEG-derived indices such as bispectral index. However, there was no controlled study that demonstrates the difference of analgesic potency. The aim of this clinical trial is to evaluate the difference of analgesic potency of sevoflurane and desflurane at equi-minimum alveolar concentration using a surgical pleth index.

Conditions

• Orthopedic Disorders

Interventions

Type	Name	Description
DRUG	Sevoflurane	Anesthesia was maintained with sevoflurane in patients undergoing arthroscopic shoulder surgery under general anesthesia and interscalene brachial plexus block.
DRUG	Desflurane	Anesthesia was maintained with desflurane in patients undergoing arthroscopic shoulder surgery under general anesthesia and interscalene brachial plexus block.

Timeline

• Start date: 2015-11-01
• Primary completion: 2016-07-28
• Completion: 2016-07-28
• First posted: 2015-11-20
• Last updated: 2017-11-08

Locations

1 site across 1 country: South Korea